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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
10 DPC

12 matching records from 12 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Gli3  GLI-Kruppel family member GLI3   (Synonyms: Bph, brachyphalangy)
Results  Reference
1J:207610 Akiyama R, Kawakami H, Taketo MM, Evans SM, Wada N, Petryk A, Kawakami Y, Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the beta-catenin pathway. Dev Biol. 2014 Mar 1;387(1):37-48
1J:220960 Akiyama R, Kawakami H, Wong J, Oishi I, Nishinakamura R, Kawakami Y, Sall4-Gli3 system in early limb progenitors is essential for the development of limb skeletal elements. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5075-80
1J:159210 Galli A, Robay D, Osterwalder M, Bao X, Benazet JD, Tariq M, Paro R, Mackem S, Zeller R, Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet. 2010;6(4):e1000901
1J:312493 Jhanwar S, Malkmus J, Stolte J, Romashkina O, Zuniga A, Zeller R, Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development. Nat Commun. 2021 Sep 28;12(1):5685
1J:69771 Lewis PM, Dunn MP, McMahon JA, Logan M, Martin JF, St-Jacques B, McMahon AP, Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell. 2001 Jun 1;105(5):599-612
1*J:213418 Li D, Sakuma R, Vakili NA, Mo R, Puviindran V, Deimling S, Zhang X, Hopyan S, Hui CC, Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling. Dev Cell. 2014 Apr 28;29(2):233-40
1*J:80020 Marcil A, Dumontier E, Chamberland M, Camper SA, Drouin J, Pitx1 and Pitx2 are required for development of hindlimb buds. Development. 2003 Jan;130(1):45-55
1J:103158 Moribe H, Takagi T, Kondoh H, Higashi Y, Suppression of polydactyly of the Gli3 mutant (extra toes) by deltaEF1 homozygous mutation. Dev Growth Differ. 2000 Aug;42(4):367-76
1*J:50307 Takahashi M, Tamura K, Buscher D, Masuya H, Yonei-Tamura S, Matsumoto K, Naitoh-Matsuo M, Takeuchi J, Ogura K, Shiroishi T, Ogura T, Belmonte JC, The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development [published erratum appears in Development 1998 Dec;125(23):preceding 4595]. Development. 1998 Nov;125(22):4417-25
1J:77675 te Welscher P, Fernandez-Teran M, Ros MA, Zeller R, Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev. 2002 Feb 15;16(4):421-6
1J:109476 Veltmaat JM, Relaix F, Le LT, Kratochwil K, Sala FG, van Veelen W, Rice R, Spencer-Dene B, Mailleux AA, Rice DP, Thiery JP, Bellusci S, Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes. Development. 2006 Jun;133(12):2325-35
1J:170090 Xu B, Wellik DM, Axial Hox9 activity establishes the posterior field in the developing forelimb. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4888-91

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory